Research
IGF-1 LR3 Research Profile: Anabolic Signalling Studies
"IGF-1 LR3 is a long-acting IGF-1 analogue with an extensive research profile in anabolic signalling biology."
IGF-1 Long R3 is a recombinant analogue of insulin-like growth factor 1 incorporating an arginine substitution at position 3 and a 13 amino acid N-terminal extension. These modifications reduce binding to IGF binding proteins, extending the half-life significantly compared to native IGF-1. Research has examined its effects on muscle satellite cell proliferation, protein synthesis signalling via mTOR pathway activation and glucose metabolism in various research models.
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